Challenges with lyophilization
Freeze-drying in an open container entails a few risks.
Dry powder flies out, generates product loss and poses a risk to the lab personnel. Particles or airborne germs are a contamination hazard to your API. Cleaning validation between different batches is required to prevent cross contamination.
Our key to safe lyophilization - the Lyoprotect® product line.
During sublimation, the vapor escapes smoothly through the hydrophobic membrane. All our products prevent fly-out and cross-contamination in your freeze dryer. The membrane acts as a sterile barrier and ensures optimum protection of staff and product.
Safeguard Staff & Product
Zero fly-out, no cross-contamination, particles and germs stay outside
Use Full Capacity
Customized solutions to perfectly fit the footprint of your freeze dryer
Save Money
No product loss, minimal investments for GMP manufacturing
Features
What makes Lyoprotect® products so special?
Safe, efficient sublimation without fly-out, contamination or cleaning validation for the freeze dryer.
Our products can be custom-made for your individual requirements and footprint.
Product range facilitates upscaling from R&D to GMP production level.
Finding the most cost-effective solution for your application is our mission.
Multiple-use solutions for better sustainability.
Exceptional quality made in Germany.
Testimonials
What do people say about the Lyoprotect® Products?
Using the customized Lyoprotect® Bags improves not only product handling but also staff safety with regard to fly-out. The various Lyoprotect® Bag sizes allow for maximum flexibility with different batch sizes and fillings - both equally important for our service and product business.
CEO at Numaferm
We have expanded our performance spectrum and can now lyophilize highly toxic custom-order APIs in our laboratory in Hanau, Germany, in compliance with GMP. The Lyoprotect® Cup with Membrane is a principal item of the freeze-drying process.
of Heraeus Pharmaceutical Ingredients BL
We'd already tried out several sterilization bags, but always had to compromise on the drying parameters. With Lyoprotect® Bags our drying philosophy of the Single-Step-Cycle can now be realized much better - we also consider the Lyoprotect® system fit for GMP production of lyophilized drugs.
Managing Director at ProJect Pharmaceutics
Mr Hofbauer concluded that contamination-free lyophilization products can be obtained by using the Lyoprotect® Tray: “With Lyoprotect® we can now freeze-dry different formulations together in the same cycle. This saves a considerable amount of time when developing product variants for our customers.”
R&D at Lactosan
Especially in the DSP development phase, the flexibility regarding bag sizes as well as the rapid availability were decisive factors... Since open handling with enzyme dusts were viewed as critical, the Lyoprotect® Bags were the ideal solution. For some time now, we have routinely employed these bags for the lyophilization of enzyme test batches and in process optimization.
Project manager at Cilian
FAQs
Frequently asked questions
All Lyoprotect® products can be sterilized in an autoclave at 121°C for 20 minutes. Sterilization with EtO and VHP is also possible for all products.
