Challenges with open trays
Do you encounter problems with lyophilization in open trays?
Freeze-drying in an open container entails a few risks. Dry powder escapes, leading to product loss and safety concerns. There is a risk of product contamination, and your freeze dryer may require cleaning validations between different batches.
Features of the Lyoprotect® Aluminum Tray
Sustainability
Reduce waste by opting for multiple-use components. The aluminum tray has a very long lifetime, only the corresponding single-use membrane must be discarded.
Safe sublimation
The Lyoprotect® Membrane acts as a sterile barrier and ensures zero fly-out. Vapor effortlessly passes through the hydrophobic membrane, which supports fast drying.
Optimum heat transfer
Aluminum has an exceptionally good heat transfer rate. The high performance between freeze dryer shelf and aluminum tray bottom provides for fast freeze-drying.
High quality
Made from aluminum AlMg 4.5 Mn. The anodized surface makes the tray suitable for multiple use. All trays are manufactured in Germany. Work’s test certificate 3.1.
Sterilization
All components including the membrane are suited for sterilization in an autoclave at 121°C (250°F) for 20 minutes. APIs can be aseptically produced in compliance with GMP.
Process development
Combine the Aluminum Tray with the smaller Cup for a continuous process development from 10 ml up to 500 ml. Ideal for R&D and small batches. Preliminary freezing is possible.
Lyoprotect® Aluminum Tray
Anodized aluminum tray with excellent heat transfer rate and ePTFE membrane for safe lyophilization
COMPLETE VIEW
Setup of a Lyoprotect® Aluminum Tray. Click below for more information about the individual components.
FIXING FRAME WITH NUTS
FILLER ASSEMBLY
MEMBRANE
GASKET
TRAY
Functional Claims
Bacteria-proof container with vapor-permeable membrane
Very high sublimation rate
No fly-out
No cross-contamination
Preliminary freezing
Safe compliance with occupational exposure limits (OEL 100 ng/m³) with flexible isolators
Quality Claims
100% visual inspection of membrane and components
Serial number and work’s test certificate 3.1 for aluminum material
Full traceability and receiving inspection of the membrane with FTIR spectrometer
Membrane is BSE/TSE safe and complies with (EU) No 10/2011 regarding food safety
Made in Germany
Dimensions
| Product name | Material | Dimensions | Volumes |
|---|---|---|---|
| LMPU-VM-W | AlMg 4.5 Mn | 158 x 222 x 41 mm | 100–500 ml |
Useful resources
Related Products
Lyoprotect® Aluminum Trays require the Lyoprotect® Membrane and Gasket in order to work properly as barrier during lyophilization.
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