Challenges with open trays
Do you encounter problems with lyophilization in open trays?
Freeze-drying in an open container entails a few risks. Dry powder escapes, leading to product loss and safety concerns. There is a risk of product contamination, and your freeze dryer may require cleaning validations between different batches.
Features of the Lyoprotect® Stainless Steel Trays
Sustainability
Reduce waste by opting for multiple-use components. The sturdy stainless steel tray has a very long lifetime, only the corresponding single-use membrane must be discarded.
Safe sublimation
The Lyoprotect® Membrane acts as a sterile barrier and ensures zero fly-out. Vapor effortlessly passes through the hydrophobic membrane, which supports fast drying.
Easy cleaning
Stainless steel trays are resistant against harsh cleaning substances. Laser-welded 45° corners and the polished surface facilitate residue-free cleaning.
High quality
High-grade stainless steel ANSI 316 L (1.4404) makes the tray suitable for a broad range of applications. All trays are manufactured in Germany and have an exceptionally plane bottom. Work’s test certificate 3.1.
Sterilization
All components including the membrane are suited for sterilization in an autoclave at 121°C (250°F) for 20 minutes. APIs can be aseptically produced in compliance with GMP.
Process Development
Our stainless steel products in various sizes allow for a continuous process development from 10 ml in R&D up to a filling volume of 6000 ml on a GMP production level. Preliminary freezing is possible, trays are stackable.
Lyoprotect® Stainless Steel Trays
High-grade stainless steel trays with ePTFE membrane for safe lyophilization without contamination or fly-out
COMPLETE VIEW
Setup of a Lyoprotect® Stainless Steel Tray. Click below for more information about the individual components.
FIXING FRAME WITH NUTS
FILLER ASSEMBLY
MEMBRANE
GASKET
TRAY
Functional Claims
Bacteria-proof container with vapor-permeable membrane
Very high sublimation rate
No fly-out
No cross-contamination
Preliminary freezing with stackable trays
Safe compliance with occupational exposure limits (OEL 100 ng/m³) with flexible isolators
Quality Claims
100% visual inspection of membrane and components
Serial number and work’s test certificate 3.1 for stainless steel plates
Lot release test (tightness test)
Full traceability and receiving inspection of the membrane with FTIR spectrometer
Membrane is BSE/TSE safe and complies with (EU) No 10/2011 regarding food safety
Made in Germany
Dimensions
| Product name | Material | Dimensions | Volumes |
|---|---|---|---|
| LMPU-V1622B-WS | stainless steel ANSI 316 L (1.4404) | 155 x 224 x 43 mm | 100–500 ml |
| LPMU-V2740B-WS | stainless steel ANSI 316 L (1.4404) | 270 x 400 x 43 mm | 400–1800 ml |
| LPMU-Vxxxx-WS | stainless steel ANSI 316 L (1.4404) | customizable, max. 400 x 700 x 53 mm | up to 6000 ml |
Useful resources
Related Products
Lyoprotect® Stainless Steel Trays require the Lyoprotect® Membrane and Gasket in order to work properly as barrier during lyophilization.
Interested?
Send us a message.
Feel free to reach out with any questions.
We're here to assist you in finding the optimal solution for your specific needs.